|
TMPY-03356
|
IFN gamma Protein, Mouse, Recombinant
IFN γ,interferon, γ,interferon, gamma,Ifg,...
|
Mouse
|
HEK293 Cells
|
|
IFN gamma Protein, Mouse, Recombinant is expressed in HEK293 mammalian cells. The predicted molecular weight is 15.5 kDa and the accession number is A0A7R8C347. |
|
TMPY-01714
|
IFN gamma Protein, Human, Recombinant
IFI,interferon, γ,IFN γ,IFG,IFN gamma<...
|
Human
|
CHO Cells
|
|
IFN gamma Protein, Human, Recombinant is expressed in CHO mammalian cells. The predicted molecular weight is 16.7 kDa and the accession number is A0A7R8GUN6. |
|
TMPY-06983
|
IFN gamma Protein, Human, Recombinant (E. coli)
Interferon Gamma,IFN γ,IFN ga...
|
Human
|
E. coli
|
|
IFN gamma, also known as IFNG, is a secreted protein that belongs to the type II interferon family. IFN gamma is produced predominantly by natural killer and natural killer T cells as part of the innate immune response, and by CD4 and CD8 cytotoxic T lymphocyte effector T cells once antigen-specific immunity develops. IFN gamma has antiviral, immunoregulatory, and anti-tumor properties. IFNG, in addition to having antiviral activity, has important immunoregulatory functions, it is a potent activ... |
|
TMPK-00047
|
IFN gamma Protein, Human, Recombinant (His & Avi)
IFN gamma,interferon,Interferon-γ,γ,IFI,干扰...
|
Human
|
HEK293 Cells
|
|
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi ... |
|
TMPY-02827
|
IFN gamma Protein, Rat, Recombinant (hFc)
interferon, γ,干扰素,interferon, gamma,IFN γ
|
Rat
|
HEK293 Cells
|
|
IFN gamma Protein, Rat, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01581. |
|
TMPY-02323
|
IFN gamma Protein, Mouse, Recombinant (His)
IFN-g,Ifg,干扰素,interferon, γ,interferon, gamma
|
Mouse
|
HEK293 Cells
|
|
IFN gamma Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 17 kDa and the accession number is P01580. |
|
TMPY-02322
|
IFN gamma Protein, Mouse, Recombinant (hFc)
IFN γ,Ifg,IFN-g,interferon, gamma...
|
Mouse
|
HEK293 Cells
|
|
IFN gamma Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 42.5 kDa and the accession number is P01580. |
|
TMPY-03664
|
IFN gamma Protein, Ferret, Recombinant (His)
interferon, gamma,interferon, γ,IFN γ,干扰素
|
Ferret
|
HEK293 Cells
|
|
IFN gamma Protein, Ferret, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 25.4 kDa and the accession number is A4PIZ9. |
|
TMPY-00527
|
IFN gamma Protein, Rhesus, Recombinant
interferon, gamma,干扰素,IFN γ,interferon, γ
|
Rhesus
|
E. coli
|
|
IFN gamma Protein, Rhesus, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 16.9 kDa and the accession number is G7N7K9. |
|
TMPK-00048
|
IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated
IFNγ,IFN γ/IFNG,gamma,γ,...
|
Human
|
HEK293 Cells
|
|
Interferon-gamma (IFN gamma) is a cytokine that plays physiologically important roles in promoting innate and adaptive immune responses. The absence of IFN gamma production or cellular responsiveness in humans and experimental animals significantly predisposes the host to microbial infection, a result that validates the physiologic importance of this cytokine in preventing infectious disease. IFN gamma Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells w... |
|
TMPY-04191
|
IFN gamma Protein, Rhesus, Recombinant (His)
interferon, γ,IFN γ,干扰素,interferon, gamma
|
Rhesus
|
HEK293 Cells
|
|
IFN gamma Protein, Rhesus, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 18.2 kDa and the accession number is G7N7K9. |
|
TMPY-02355
|
IFNGR1 Protein, Mouse, Recombinant (His)
interferon gamma receptor 1,Nktar,interferon γ rece...
|
Mouse
|
HEK293 Cells
|
|
IFNGR1 Protein, Mouse, Recombinant (His) is expressed in HEK293 mammalian cells with His tag. The predicted molecular weight is 27.4 kDa and the accession number is P15261. |
|
TMPH-00373
|
IFN gamma Protein, Chicken, Recombinant (GST)
|
Chicken
|
E. coli
|
|
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. IFN gamma Protein, Chicken, Recombinant (GST) is expressed in E. coli expression system with N-GST tag. The predicted molecular weight is 43.7 kDa and the ac... |
|
TMPH-03495
|
IFN gamma Protein, Sheep, Recombinant (His)
|
Sheep
|
P. pastoris (Yeast)
|
|
IFN gamma Protein, Sheep, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.9 kDa and the accession number is P17773. |
|
TMPH-00775
|
IFN gamma Protein, Goat, Recombinant (His & Myc)
|
Goat
|
E. coli
|
|
Type II interferon produced by immune cells such as T-cells and NK cells that plays crucial roles in antimicrobial, antiviral, and antitumor responses by activating effector immune cells and enhancing antigen presentation. Primarily signals through the JAK-STAT pathway after interaction with its receptor IFNGR1 to affect gene regulation. Upon IFNG binding, IFNGR1 intracellular domain opens out to allow association of downstream signaling components JAK2, JAK1 and STAT1, leading to STAT1 activati... |
|
TMPJ-01056
|
IL-18 Protein, Mouse, Recombinant (His)
Interferon γ-inducing factor,Interleukin-1 gamma,Ig...
|
Mouse
|
E. coli
|
|
Interleukin-18 (IL-18）is a protein which belongs to the IL-1 family. It is expressed as a 24 kDa precursor by endothelial and epithelial cells, keratinocytes, gamma δ T cells, and phagocytes. Mature mouse IL-18 shares 63% and 91% amino acid sequence identity with mouse and rat IL-18, respectively. IL-18 binds to the widely expressed IL-18 R alpha which recruits IL-18 R beta to form the signaling receptor complex. Its bioactivity is negatively regulated by interactions with IL-18 binding proteins... |
|
TMPY-02354
|
IFNGR1 Protein, Mouse, Recombinant (hFc)
IFN-gammaR,Ifgr,interferon γ receptor 1,
|
Mouse
|
HEK293 Cells
|
|
IFNGR1 Protein, Mouse, Recombinant (hFc) is expressed in HEK293 mammalian cells with hFc tag. The predicted molecular weight is 53 kDa and the accession number is P15261. |
|
TMPH-00778
|
IFN gamma Protein, Guinea Pig, Recombinant (His)
|
Guinea pig
|
E. coli
|
|
IFN gamma Protein, Guinea Pig, Recombinant (His) is expressed in E. coli. |
|
TMPH-02451
|
IFN gamma Protein, Marmota monax, Recombinant (His)
|
Marmota monax
|
P. pastoris (Yeast)
|
|
Produced by lymphocytes activated by specific antigens or mitogens. IFN-gamma, in addition to having antiviral activity, has important immunoregulatory functions. It is a potent activator of macrophages, it has antiproliferative effects on transformed cells and it can potentiate the antiviral and antitumor effects of the type I interferons. IFN gamma Protein, Marmota monax, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 18.6 kDa and the accession numb... |
|
TMPH-03494
|
IFN gamma Protein, Sheep, Recombinant (E. coli, His)
|
Sheep
|
E. coli
|
|
IFN gamma Protein, Sheep, Recombinant (E. coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 20.9 kDa and the accession number is P17773. |
|
TMPJ-00070
|
IL-18 Protein, Human, Recombinant (His)
GIF,IL-1 γ,白细胞介素,Iboctadekin,Interleukin-18,Interferon γ-ind...
|
Human
|
HEK293 Cells
|
|
Interleukin-18 is a secreted protein and it belongs to the IL-1 family. IL-18 is a proinflammatory cytokine and produced by macrophages and other cells. This cytokine can induce the IFN-gamma production of T cells. The combination of this cytokine and IL12 has been shown to inhibit IL-4 dependent IgE and IgG1 production, and enhance IgG2a production of B cells. IL-18 binding protein (IL18BP) can specifically interact with this cytokine, and thus negatively regulate its biological activity. After... |
|
TMPY-01648
|
TREML2 Protein, Human, Recombinant (His)
TLT2,dJ238O23.1,triggering receptor expressed on myeloid cel...
|
Human
|
HEK293 Cells
|
|
Trem-like transcript 2 protein, also known as Triggering receptor expressed on myeloid cells-like protein 2, TREML2 and TLT2, is a single-pass type I membrane protein that contains one Ig-like V-type (immunoglobulin-like) domain. TREML2 is detected in cultured B cells, T cell leukemia and monocyte leukemia. TREML2 is expressed constitutively on CD8 T-cells and induced on CD4 T-cells after activation. TREML2 is a cell surface receptor that may play a role in the innate and adaptive immune respons... |
|
TMPY-02240
|
STAT1 Protein, Human, Recombinant (His & GST)
IMD31A,IMD31B,IMD31C,STAT91,CANDF7,signal transducer and act...
|
Human
|
Baculovirus Insect Cells
|
|
STAT1 is a member of the STAT protein family. In response to cytokines and growth factors, STAT family members are phosphorylated by the receptor-associated kinases, and then form homo- or heterodimers that translocate to the cell nucleus where they act as transcription activators. STAT1 can be activated by various ligands, including interferon-alpha, interferon-gamma, EGF, PDGF and IL6. It is a signal transducer and transcription activator that mediates cellular responses to interferons (IFNs),... |
|
TMPJ-00961
|
STAT1 Protein, Human, Recombinant
Transcription Factor ISGF-3 Components p91/p84,STAT1,Signal ...
|
Human
|
E. coli
|
|
Signal Transducer and Activator of Transcription 1-Alpha/Beta (STAT1) contains one SH2 domain and belongs to the transcription factor STAT family. When tyrosine- and serine-phosphorylated, STAT1 can form a homodimer termed IFN-gamma-activated factor (GAF), migrate into the nucleus and bind to the IFN gamma activated sequence (GAS) to drive the expression of the target genes, inducing a cellular antiviral state. STAT1 functions as signal transducer and transcription activator that mediates cellul... |
|
TMPH-02272
|
JAK1 Protein, Human, Recombinant (E. coli, His)
|
Human
|
E. coli
|
|
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors. |
|
TMPH-02273
|
JAK1 Protein, Human, Recombinant (His)
|
Human
|
P. pastoris (Yeast)
|
|
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors. |
|
TMPK-01016
|
B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled
B7H3, UNQ309,PRO352,PSEC0249,B7 homolog 3,B7-H3,CD276
|
Human
|
HEK293 Cells
|
|
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (hFc), FITC-Labeled is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular w... |
|
TMPK-00314
|
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi)
B7-H3,PSEC0249,PRO352, 4Ig-B7-H3,B7 homolog 3,UNQ309,CD276
|
Human
|
HEK293 Cells
|
|
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi) is expressed in HEK293 mammalian cells with C-His-Avi tag. The predicted m... |
|
TMPK-01017
|
B7-H3 Protein, Human, Recombinant (aa 29-245, hFc)
B7H3,B7-H3,B7 homolog 3,PSEC0249,CD276,PRO352, UNQ309
|
Human
|
HEK293 Cells
|
|
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, hFc) is expressed in HEK293 mammalian cells with C-hFc tag. The predicted molecular weig... |
|
TMPK-00315
|
B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated
4Ig-B7-H3,CD276,UNQ309,B7-H3,PRO352,PSEC0249,B7 homolog 3
|
Human
|
HEK293 Cells
|
|
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 (4Ig) /B7-H3b Protein, Human, Recombinant (His & Avi), Biotinylated is expressed in HEK293 mammalian cells with C-His-Avi tag. T... |
|
TMPK-01018
|
B7-H3 Protein, Human, Recombinant (aa 29-245, His)
PRO352,B7H3, UNQ309,PSEC0249,CD276,B7-H3,B7 homolog 3
|
Human
|
HEK293 Cells
|
|
B7-H3, a member of the B7 family of immunomodulatory molecules, is overexpressed in a wide range of solid cancers.B7-H3 binds to activated T cells via an as yet unidentified receptor. In assays using sub-optimal amount so anti-CD3 stimulation, 2Ig‑B7‑H3 enhances T cell proliferation, T cell interferon-gamma (IFN-gamma) production, and cytotoxic T cells induction. B7-H3 Protein, Human, Recombinant (aa 29-245, His) is expressed in HEK293 mammalian cells with C-His tag. The predicted molecular weig... |
|
TMPH-01558
|
IL12RB2 Protein, Human, Recombinant (His)
|
Human
|
P. pastoris (Yeast)
|
|
Receptor for interleukin-12. This subunit is the signaling component coupling to the JAK2/STAT4 pathway. Promotes the proliferation of T-cells as well as NK cells. Induces the promotion of T-cells towards the Th1 phenotype by strongly enhancing IFN-gamma production. IL12RB2 Protein, Human, Recombinant (His) is expressed in yeast with N-6xHis tag. The predicted molecular weight is 69.7 kDa and the accession number is Q99665. |
|
TMPH-00550
|
Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc)
|
EBV
|
E. coli
|
|
Plays a role in masking infected cells for immune recognition by cytotoxic T-lymphocytes. Down-regulates the expression of the host TAP1 gene (transporter associated with antigen processing), thereby affecting the transport of peptides into the endoplasmic reticulum and subsequent peptide loading by MHC class I molecules. Inhibits IFN-gamma synthesis. Epstein-Barr virus (strain B95-8) BCRF1 Protein (His & Myc) is expressed in E. coli expression system with N-10xHis and C-Myc tag. The predicted m... |
|
TMPJ-00074
|
IL-18BP Protein, Human, Recombinant (hFc)
Interleukin-18-binding protein,Tadekinig-alfa and IL18BP
|
Human
|
HEK293 Cells
|
|
Interleukin-18-binding protein, also known as Tadekinig-alfa and IL18BP, contains 1 Ig-like C2-type domain. IL18BP is constitutively expressed and secreted in mononuclear cells. IL18BP functions as an IL18 inhibitor. IL18BP binds to IL18, prevents the binding of IL18 to its receptor, and thus inhibits IL18-induced IFN-gamma production. It has been shown that IL18BP may be a promising molecular approach to inhibit neointimal hyperplasia and arteriosclerosis progression following coronary and peri... |
|
TMPH-02961
|
JAK1 Protein, Mouse, Recombinant (His)
|
Mouse
|
E. coli
|
|
Tyrosine kinase of the non-receptor type, involved in the IFN-alpha/beta/gamma signal pathway. Kinase partner for the interleukin (IL)-2 receptor as well as interleukin (IL)-10 receptor. Directly phosphorylates STAT but also activates STAT signaling through the transactivation of other JAK kinases associated with signaling receptors. JAK1 Protein, Mouse, Recombinant (His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 39.1 kDa and the accession numb... |
|
TMPJ-00930
|
VCAM-1 Protein, Mouse, Recombinant (hFc)
Vascular cell adhesion protein 1,Vcam1
|
Mouse
|
HEK293 Cells
|
|
Vascular cell adhesion molecule 1 (VCAM-1) is a cell surface protein belonging to the immunoglobulin superfamily, the protein is expressed by activated endothelial cells and certain leukocytes (such as macrophages). IL-1 beta, IL-4, TNF-alpha and IFN-gamma induced the expression of VCAM-1. The human and mouse VCAM-1 proteins share approximately 76% amino acid similarity. Mouse VCAM-1 is Important in cell-cell recognition. it appears to function in leukocyte-endothelial cell adhesion, and interac... |
|
TMPY-03122
|
GBP2 Protein, Human, Recombinant (His)
guanylate binding protein 2,GBP2
|
Human
|
HEK293 Cells
|
|
GBP-2 belongs to the guanylate-binding protein (GBP) family. GBPs are characterized by their ability to specifically bind guanine nucleotides (GMP, GDP, and GTP). As GTPases induced by IFN-gamma (Interferon-inducible GTPase), they are key to the protective immunity against microbial and viral pathogens. GBP-2 is a GTPase that converts GTP to GDP and GMP. It binds GTP, GDP and GMP. GBP-2 hydrolyzes GTP very efficiently. GDP rather than GMP is the major reaction product. GBP-2 is induced by interf... |
|
TMPY-02122
|
IFNGR2 Protein, Mouse, Recombinant (His)
interferon γ receptor 2 (interferon γ transducer 1),interfer...
|
Mouse
|
HEK293 Cells
|
|
Interferon-gamma receptor beta chain (IFNgammaR2), also known as IFNGR2, belongs to the type II cytokine receptor family, whose deficiency is a cause of autosomal recessive mendelian susceptibility to mycobacterial disease (MSMD), also known as familial disseminated atypical mycobacterial infection. This accessory factor is an integral part of the IFN-gamma signal transduction pathway and is likely to interact with GAF, JAK1, and/or JAK2. IFNGR2 is a component of the IFNgamma receptor complex al... |
|
TMPJ-00281
|
CADM1 Protein, Mouse, Recombinant (hFc)
IgSF4,NECL-2,Nectin-like protein 2,Immunoglobulin superfamil...
|
Mouse
|
HEK293 Cells
|
|
Cell adhesion molecule 1(CADM1) is a single-pass type I membrane protein and belongs to the nectin family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain. CADM1 acts as a tumor suppressor in non-small-cell lung cancer (NSCLC) cells. Interaction with CRTAM promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in... |
|
TMPJ-00438
|
SECTM1A Protein, Mouse, Recombinant (His)
Sectm1a
|
Mouse
|
HEK293 Cells
|
|
SECTM1A (secreted and transmembrane 1A), is 192 amino acid (aa) protein, appears to share structural and functional characteristics with other SECTM1 proteins. Human SECTM1 can be found either found as an approximately 27 kDa intracellular type I transmembrane protein that shows a perinuclear, Golgi like staining pattern, or as a 20 kDa soluble, secreted form, and is produced by some myeloid cells and by thymic epithelia and fibroblasts. Stimulation with IFN gamma is often necessary to detect h... |
|
TMPH-02274
|
JAK2 Protein, Human, Recombinant (His)
|
Human
|
E. coli
|
|
Non-receptor tyrosine kinase involved in various processes such as cell growth, development, differentiation or histone modifications. Mediates essential signaling events in both innate and adaptive immunity. In the cytoplasm, plays a pivotal role in signal transduction via its association with type I receptors such as growth hormone (GHR), prolactin (PRLR), leptin (LEPR), erythropoietin (EPOR), thrombopoietin (THPO); or type II receptors including IFN-alpha, IFN-beta, IFN-gamma and multiple int... |
|
TMPJ-00226
|
SLAMF1 Protein, Mouse, Recombinant (His)
signaling lymphocytic activation molecule,SLAM family member...
|
Mouse
|
HEK293 Cells
|
|
Signaling lymphocyte activation molecule (SLAM), is a self-ligand glycoprotein which exists not only found on the surface of activated and memory T cells, but also on the surface of activated B cells, dendritic cells, and macrophages. SLAM consists of a extracellular domain (ECD) with two Ig-like domains,transmembrane segment, and cytoplasmic domain with three immunoreceptor tyrosine switch motifs (ITSM). SLAM is thought to play an important role in adhesion between T cells and APCs and has been... |
|
TMPY-04408
|
CAMKII beta/CAMK2B Protein, Human, Recombinant (His & GST)
calcium/calmodulin-dependent protein kinase II beta,CAM2,CAM...
|
Human
|
Baculovirus Insect Cells
|
|
Calcium/calmodulin-dependent protein kinase II beta (CAMK2B) is a member of the serine/threonine protein kinase family and to the Ca(2+)/calmodulin-dependent protein kinase subfamily. CaMKII is an important player in prostate cancer cells ability to escape apoptosis under androgen ablation and facilitate the progression of prostate cancer cells to an androgen independent state. As a multifunctional protein kinase, the loss of activity may play a critical role in initiating the changes leading to... |
|
TMPH-02632
|
TRIM21 Protein, Mouse, Recombinant (E. coli, His)
|
Mouse
|
E. coli
|
|
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr... |
|
TMPH-02633
|
TRIM21 Protein, Mouse, Recombinant (His)
|
Mouse
|
Baculovirus Insect Cells
|
|
E3 ubiquitin-protein ligase whose activity is dependent on E2 enzymes, UBE2D1, UBE2D2, UBE2E1 and UBE2E2. Forms a ubiquitin ligase complex in cooperation with the E2 UBE2D2 that is used not only for the ubiquitination of USP4 and IKBKB but also for its self-ubiquitination. Component of cullin-RING-based SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complexes such as SCF(SKP2)-like complexes. A TRIM21-containing SCF(SKP2)-like complex is shown to mediate ubiquitination of CDKN1B ('Thr... |
|
TMPY-02045
|
SECTM1 Protein, Human, Recombinant (His)
K12,secreted and transmembrane 1
|
Human
|
HEK293 Cells
|
|
Secreted and transmembrane 1 (SECTM1), also known as K12, is a transmembrane and secreted protein with characteristics of a type 1a transmembrane protein of SECTM family. It is found in a perinuclear Golgi-like pattern and thought to be involved in hematopoietic and/or immune system processes. The human K12 protein has been shown to be primarily expressed in spleen, prostate, testis, small intestine, and in peripheral blood leukocytes. The K12 protein is expressed on the cell surface in such sma... |
|
TMPJ-00359
|
SLAMF3 Protein, Human, Recombinant (His)
Signaling lymphocytic activation molecule 3,CD229,Cell surfa...
|
Human
|
HEK293 Cells
|
|
SLAMF3 (CD229) is a type I transmembrane glycoprotein in the SLAM subgroup of the CD2 family. Mature human SLAMF3 consists of a 407 amino acid (aa) extracellular domain (ECD) with two Ig-like V-set and two Ig-like truncated C2-set domains. The ECD of human SLAMF3 shares 57% - 59% aa sequence identity with mouse and rat SLAMF3. Within the first two Ig-like domains that are common to all SLAM proteins, human SLAMF3 shares 24% - 39% aa sequence identity with human 2B4, BLAME, CD2F-10, CD84, CRACC, ... |
沪公网安备 31010602006700号